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HOME >> Research and Development >> Renal Replacement Therapy Abstract of paper published in June, 2016
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Abstracts of Scientific Papers
PLOS ONE
(September 2017)
PLOS ONE
(February 2017)
Renal Replacement Therapy
(June 2016)
Environmental Control
In Biology
(July 2014)
Medical Gas Research
(December 2013)
Hemodial International
(November 2013)
PLoS ONE
(July 2012)
Cytotechnology
(June 2012)
Trends in Food Science and Technology
(November 2011)
BMC Proceedings
(November 2011)
BMC Proceedings
(November 2011)
Bioscience,
Biotechnology,
and Biochemistry
(July 2011)
Nephrology Dialysis Transplantation
(December 2010)
Cytotechnology
(November 2010)
Bioscience,
Biotechnology,
and Biochemistry
(October 2010)
Nephrology Dialysis Transplantation
(April 2010)
Nephrology Dialysis Transplantation
(February 2010)
Free Radical Research
(January 2010)
Nephron Clinical Practice
(April 2009)
Langmuir
(June 2008)
Biological & Pharmaceutical Bulletin
(January 2008)
Hemodialysis International
(June 2007)
Kidney International
(July 2006)
Cytotechnology
(January 2005)
Kidney International
Vol.64 (July 2003)
Cytotechnology
(June 2003)
BBRC
(BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS)
(May 1997)
List of Papers and Conference Presentations on Electrolyzed Reduced Water
What is electrolyzed reduced water?
Environmental Control In Biology (2014) Abstract of paper published in July 2014
Effects of Deoxidized Nutrient Solution on Growth of Komatsuna (Brassica rapa var. perviridis) Plants

Increased oxidative stress and pro-inflammatory conditions, commonly present in chronic dialysis patients, are thought to be enhanced during hemodialysis (HD) and to be associated with the excess morbidity and mortality seen in these patients. The hydrogen molecule (H2) has a unique biological capacity to act as an antioxidative and anti-inflammatory substance. In light of accumulating evidence from animal studies showing protective effects against organ damage during ischemia and inflammation, development of H2 treatments for HD patients has become a challenging clinical goal.

An HD system utilizing a water electrolysis technique that renders large amounts of H2-enriched water has been developed. During HD with an H2-enriched solution (approximately 50 ppb H2), markers of increased oxidative stress (such as interleukin-6, myeloperoxidase, methemoglobin, increased lymphocyte apoptosis, and high blood pressure) are suppressed. These findings indicate that the use of an H2-enriched solution may prove to be a novel approach to ameliorate dialysis-related complications. This manuscript reviews the recent progress in H2 research and the use of H2 in HD patients, including a description of a water electrolysis technique that delivers large amounts of H2-enriched water for use in clinical settings.

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