R & DCollaborative Research & Regional Partnerships

Collaborative Research

In order to unlock new possibilities and applications for electrolyzed hydrogen water, Nihon Trim engages in collaborative research with domestic and international universities and research institutions. Together, we are uncovering the limitless potential of electrolyzed hydrogen water.

» Learn more about past research collaborations

Tohoku University Hospital

  • Department for collaborative research on hemodialysis treatment for chronic kidney diseases

    • Medicine

    Research and development of treatment methods using electrolytic technology for patients with renal failure

    Published Articles
    Novel haemodialysis (HD) treatment employing molecular hydrogen (H2)-enriched dialysis solution improves prognosis of chronic dialysis patients: A prospective observational study (Published in the British journal Scientific Reports)
    Possible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients: Interim analysis in a 12 month observation (Published in the American journal PLOS ONE)

Tohoku University Graduate School

  • Graduate School of Medicine

    • Medicine

    Research on antidiabetic treatments using electrolyzed hydrogen water

University of Tokyo Graduate School

  • Graduate School of Engineering

    • Basic Research

    Research to identify the physical properties of electrolyzed hydrogen water

Waseda University

  • Graduate School of Human Sciences

    • Basic Research

    Identifying the mechanisms of action in electrolyzed hydrogen water

National Research and Development Agency Riken

  • Riken

    • Basic Research

    Research on the antioxidant, anti-inflammatory and antifatigue properties of electrolyzed hydrogen water and its pharmacokinetics

Ritsumeikan University

  • College of Sport and Health Science

    • Basic Research

    Research on the physiological effects of electrolyzed hydrogen water when playing sports

Kochi University

  • Medical Department, City of Susaki in Kochi Prefecture (joint research partnership)

    • Medicine

    Research on the efficacy of electrolyzed hydrogen water in combatting metabolic syndrome

  • Faculty of Agriculture and Marine Science

    • Agriculture

    Research and development of the next-generation in facility landscaping solutions: Reduced Vegetables Project using Electrolyzed Hydrogen Water

    Published Articles
    Effects of Deoxidized Nutrient Solution on Growth of Komatsuna (Brassica rapa var.perviridis) Plants (Published in the journal Environmental Control In Biology)

Kochi National College of Technology

  • Kochi National College of Technology

    • Basic Research

    Research on electrolysis and purification

Karolinska Institute

  • Karolinska Institute

    • Basic Research

    Research on the efficacy of electrolyzed hydrogen water in combatting psychiatric disorders

    Published Articles
    Molecular Hydrogen Reduces LPS-Induced Neuroinflammation and Promotes Recovery from Sickness Behaviour in Mice (Published in the American journal PLOS ONE)

Past Research Collaborations

  • Kyushu University

    Published Articles
    Electrochemically reduced water exerts superior reactive oxygen species scavenging activity in HT1080 cells than the equivalent level of hydrogen-dissolved water (Published in the American journal PLOS ONE)
    Suppressive effects of electrolyzed reduced water on alloxan-induced apoptosis and type 1 diabetes Mellitus (Published in the Dutch journal Cytotechnology)
    Extension of the Lifespan of Caenorhabditis Elegans by Electrolyzed Reduced Water (Published in the Japan Society for Bioscience, Biotechnology, and Agrochemistry's (JSBBA) journal Bioscience, Biotechnology, and Biochemistry)
    Potential efficacy of electrolyzed hydrogen water in inhibiting oxidative damage to DNA
  • Obihiro University of Agriculture and Veterinary Medicine

    Published Articles
    Preventive Effects of Drinking Electrolyzed Hydrogen Water Against Gastric Ulcer Caused by Non-steroid Anti-inflammatory Drugs in Horses(Published in the JVM Veterinary and Animal Husbandry Bulletin)
  • National Taiwan University

    Published Articles
    Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water (Published in the American medical journal Kidney International)

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